Changes in mean weight (P=0.75), body mass index (P=0.52), and HDL-cholesterol (P=0.13) were not found to be significantly different between groups. Evening primrose oil is available in many health food stores or pharmacies and is typically sold in gel cap form. F… Best Natural Supplements and Vitamins for PCOS, DIY Vitamin C Serum – 3 Easy Homemade Recipes, Benefits of Rhodiola Rosea for Anxiety and Stress, Spirulina Face Mask: DIY Cleansing and Lifting Recipes, The Best Foot Soaks For Toenail Fungus (including DIY recipes), Top 6 Essential Oils for Nausea and Motion Sickness, 10 Spirulina Recipes That Are Actually Tasty, Evening primrose oil for menopause – reviews, dosage, and effects, What you need to know before taking Evening primrose oil to induce labor naturally, Evening Primrose Oil for Acne: “Before & After”. Some midwives may use it to ripen the cervix during the 3 rd trimester of pregnancy, in order to make it ready for delivery. What works for you may not be the best for another. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. Few adverse effects were noted in these trials, and there was no increase in blood glucose levels.43, 44, As a component of medical nutrition therapy for patients with type 2 diabetes, the American Diabetes Association Standards of Care (2014) recommends higher quality dietary fat intake, as an alternative to decreased fat intake, by replacing saturated and/or trans fats with mono- and poly-unsaturated fatty acids in the diet. Here you'll find all collections you've created before. Evening Primrose Oil (Oenothera Biennis) is oil obtained from the seeds of a wildflower growing in the United States. Meta-analyses conducted with 7 studies using participant-reported improvements (n = 176) and 8 using physician-assessed improvements (n = 289) support previous reports of the lack of effectiveness of evening primrose oil.67, While an older review suggested promising results12 the most comprehensive meta-analysis to date did not establish efficacy.10 Clinical studies continue to be conducted, with a gradual time-dependent improvement suggested.13, There is no recent evidence to support older studies38, 39, 40 suggesting that evening primrose oil reduced platelet aggregation. You should talk with your health care provider for complete information about the risks and benefits of using this product. Consider therapy modification.59, 60, 61, 62, Anticoagulants: Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of anticoagulants. Some women with breast pain might not have high enough levels of Gamma Linoleic Acid (GLA), and EPO contains one of the highest concentrations of GLA among herbal remedies. ... What is evening primrose oil? Usually, mild side effects like headache, nausea, upset stomach and loose stools, are experienced by some of the users. alcoholism. Most of these side effects can be avoided by starting the treatment in … – Different conditions require different dosages. Several studies have shown, that supplements with gamma-linolenic acid can reduce both inflammatory and non-inflammatory acne lesions. This oil has a number of medicinal uses and hence, is widely used in the management of several disorders. Warnings. The products and supplements mentioned on this site are not intended to diagnose, treat, cure, alleviate or prevent any diseases. For weight loss purposes take 3000-5000 mg of EPO daily. With high amounts of natural omega-6 fatty acids, linoleic acid, and gamma-linolenic acid (GLA), evening primrose oil inhibits the body's natural production of the chemicals which generally cause inflammation on the skin as well as in the joints. This oil has a number of medicinal uses and hence, is widely used in the management of several disorders. Evening primrose oil for eczema: no more itch? Quantitative Insulin Check Index (P=0.007) was found to be significantly different between groups.70, Topical application of saponified evening primrose oil reduced ultraviolet B-induced hyperpigmentation, while a decrease in melanin production has been demonstrated in vivo with the saponified oil.54, Local injection-site reactions after subcutaneous injections of 5-azacitidine and bortezomib have been reduced with topical application of evening primrose oil.55, 66 Additionally, the time to complete resolution of bortezomib-induced skin reactions was shortened (median, 4 days).66, There is little evidence to support the efficacy of evening primrose oil in treatment of mastalgia, with most trials finding no advantage over placebo.14, 15, 16, 17 Although 23% taking evening primrose oil experienced a complete response in a small randomized, comparator trial (n = 135) after 6 months of therapy, this response was statistically significantly less than the group receiving the study drug Centchroman, a novel nonsteroidal selective anti-estrogen oral contraceptive, which showed an 86% response (P < 0.05).65 A meta-analysis of clinical trials found no evidence of effect in pain relief, with a mean pain score difference of -2.78 (95% confidence interval, -7.97 to 2.4).18, A number of reviews and randomized clinical trials found no evidence of benefit with evening primrose oil use for menopausal vasomotor symptoms or premenstrual syndrome.19, 20, 21, 22, 23, 24, 25 In 2004, the North American Menopause Society did not support the use of evening primrose oil for menopausal vasomotor symptoms given the lack of efficacy data, but this has not been recently reviewed.26 The Society of Obstetricians and Gynaecologists of Canada revised clinical practice guidelines (2014) on managing menopause do not recommend evening primrose oil for reducing menopausal symptoms based on a lack of evidence to support clinical benefit.71 A 2013 randomized, double-blind, placebo-controlled trial in 56 menopausal treatment-naïve Iranian women (with at least 4 hot flashes a day) documented significant changes from baseline for hot flash severity, but not in their frequency or duration, in those randomized to receive 1,000 mg/day evening primrose oil extract for 6 weeks. Evening Primrose Oil. Most convenient would be to take one capsule of 1000mg per day. 14 The safety of long-term use of GLA hasn’t been established, but it may pose risks during pregnancy or for those taking other blood thinning medications. Available for Android and iOS devices. GNC Women's Evening Primrose Oil 1300mg capsules are taken daily to help keep skin smooth and healthy and support the balance of hormones within the body. The normal dose for evening primrose oil is 1000mg to 3000mg/day. Vitamin E is a fat-soluble antioxidant known for its ability to build and repair tissues . Mild self-limiting nausea was reported in 2 women in the intervention group.68. A more recent randomized, controlled trial found no effect on endothelial function or vascular tone with evening primrose oil supplementation.42, A review of 3 randomized, controlled trials suggested evening primrose oil might improve symptoms of diabetic neuropathy. When taken by mouth, it can sometimes cause mild side effects including upset stomach, nausea, diarrhea, and headache. However, it will be the doctor or nutrition specialist who recommends the most appropriate dose. Also known as "king's cure-all" or "night willow herb," evening primrose is a wildflower with medicinal properties. 1. This oil contains a fatty acid called gamma-linolenic acid, or GLA for short, as well as linoleic acid. . Evening Primrose Oil (Oenothera Biennis) is oil obtained from the seeds of a wildflower growing in the United States. 10 Best Evening Primrose Oil Supplements – Dosage and benefits, Cabbage Soup Detox for Weight Loss: 7-Day Diet Plan. All articles on this website are the opinions of their respective authors who do not claim or profess to be medical professionals providing medical advice. Often people ask themselves – how much evening primrose oil should I take? Evening primrose oil has been administered orally in clinical trials at doses between 1 and 8 g/day in adults and 2 and 4 g/day in children. Consider therapy modification.59, 60, 61, 62, Two clinical studies conducted in the 1980s among individuals with schizophrenia led to a concern that evening primrose oil might lower the seizure threshold. Mucilage and tannin in the plant parts have been analyzed.2, Essential fatty acids are important as cellular structural elements and as precursors of prostaglandins. For those who are new to aromatherapy, you may be wondering what is evening primrose oil? 9 Phenomenal Benefits Of Evening Primrose Oil For Skin, Evening Primrose Oil for PCOS – Uses, Benefits, and Side Effects. These dosages are recommended by an alternative health center but are not backed by scientific research. This information relates to an herbal, vitamin, mineral or other dietary supplement. Evening Primrose Oil Side Effects. The evening primrose is a large, delicate wildflower native to North America with blooms usually lasting only 1 evening, but it is not a true primrose. Wide-ranging doses of 0.27 g to 6.48 g GLA per day have been used in clinical studies in mastalgia.24 The typical content of GLA in the oil is 8% to 10%.2Evening primrose oil 1 g/day in combination with vitamin D3 (1,000 units/day) has been used to improve glycemic and lipid profiles in women with gestational diabetes.70 A case report exists of transient petechiae in a newborn following oral and intravaginal use of evening primrose oil for cervical ripening for a week prior to the infant's birth. If you are among those people, always consider the size of the evening primrose oil capsule. Always consult your doctor before use and start with a low dose. Evening primrose oil dosage for rheumatoid arthritis. A theoretical model has been proposed for a place in therapy for evening primrose oil in this condition. It comes from the plant Oenothera biennis and boasts high levels of fatty acids, such as gamma-linolenic acid (GLA). Evening primrose oil … We comply with the HONcode standard for trustworthy health information -. The medicinal product is produced from the plant’s seeds. 1,3 Today, this oil is commonly used as a carrier oil for essential oils but carries its own benefits, as well. Skin Health: Evening Primrose Oil contains GLA to help maintain the appearance of healthy skin and can help assist with dryness and itching associated with mild skin conditions. Trending Bleeding may occur. twice daily. The authors found the evidence to be sufficient to warrant further larger trials to provide conclusive results and define optimal dosage and duration of therapy.34 These findings are supported by other reviews, especially with regard to effective duration of therapy.35, 36 A more recent randomized, double-blind, placebo-controlled study enrolling 90 patients with primary Sjögren syndrome found no statistically significant in patient fatigue with a higher dosage after 6 months of therapy.37, An exploratory study found an increase in urinary citrate excretion following 1,000 mg/day of evening primrose oil.57, Evening primrose oil has been administered orally in clinical trials at doses between 6 and 8 g/day in adults and 2 and 4 g/day in children. Most health stores sell dietary supplements containing evening primrose oil (EPO), which is extracted from the plant's seeds. The liquid doses are usually much smaller but it can vary from product to product. GLA helps support women during the premenstrual period. An observational study suggests serum linoleic acid may protect against ischemic stroke.41 Despite limited older trials in humans and numerous studies using rats and rabbits, there are no recent randomized, controlled trials demonstrating a beneficial effect of evening primrose oil on cholesterol levels or serum lipids. Side effects, drug interactions, dosage, storage, and safety information should be reviewed prior to taking this supplement. Bleeding may occur. Evening Primrose Oil Side Effects and Dosage. The dose is calculated on the basis of a clinical study [1]. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. It may take up to six months until you see noticeable results. Either evening primrose oil is rubbed on the female’s cervix, or it is taken internally, or it is used as a vaginal suppository. Generally speaking, a daily dose of 500 milligrams is considered safe in adults, although many can tolerate up to 1,300 milligrams daily without any side effects. Like the article said, the dose should be broken up into two or three doses. It is also used for Alzheimer’s disease, arthritis and heart disease, according to … This is only a brief summary of general information about this product. Below we will reveal correct evening primrose oil dosage for hormonal acne, menopause, pregnancy, and weight loss. This website is strictly for the purpose of providing opinions of the author. It comes from the plant Oenothera biennis and boasts high levels of fatty acids, such as gamma-linolenic acid (GLA). Any and all trademarks, logos brand names and service marks displayed on this website are the registered or unregistered Trademarks of their respective owners. Even though there aren’t a lot of studies to prove … For those who are new to aromatherapy, you may be wondering what is evening primrose oil? It can help clear up acne. If you’re approaching menopause or have already entered menopause, you might be concerned about some of the symptoms, such as hot flashes and difficulty sleeping. The typical content of gamma-linolenic acid (GLA) in the oil is 8% to 10%. Among the many antioxidants in the evening primrose oil, one of the more abundant is Vitamin E. Vitamin E found in evening primrose oil may help reduce oxidative stress from free radicals in the scalp thereby reducing hair loss and stimulating hair growth. It gets its name from its yellow blossoms, which bloom in the evening. This information is not specific medical advice and does not replace information you receive from your health care provider. To moisturise skin or hair, you’ll want to use oil – or a product containing the oil – directly on your skin/hair. It is used for its natural healing properties. Evening primrose oil (EPO) is among the best treatments that can be used to relieve menopause symptoms. Evening primrose oil is extracted from the seeds of evening primrose (Oenothera biennis), a plant native to North America. Take 3,000 mg daily for the first 12 weeks to rebuild GLA stores and then 1,000 mg as a maintenance dose. Medscape - Indication-specific dosing for fever plant, kings cureall, night willow herb, oenothera biennis, scabish, stella di sera, sun drop (evening primrose oil), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. The supplement contains the fatty acid gamma-linolenic acid (GLA).People take evening primrose oil orally to treat a wide variety of conditions. Evening Primrose Oil Dosage – for Acne, Menopause, Pregnancy, Click to share on Twitter (Opens in new window), Click to share on Facebook (Opens in new window), Why you absolutely need to use rosehip oil for oily skin, How to use manuka honey for eczema and cure it naturally. Bottled primrose oil is also available but is m… Evening primrose oil may cause low blood pressure. [1] Little CV, Parsons T. Herbal therapy for treating rheumatoid arthritis. In vitro and in vivo animal studies suggest inhibition of platelet function in the newborn may have been caused by exposure to evening primrose oil.58, Agents with antiplatelet roperties: Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of agents with antiplatelet properties. Consider therapy modification.59, 60, 61, 62, Herbs (anticoagulant/antiplatelet properties): Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of other herbs (anticoagulant/antiplatelet properties). Evening Primrose Oil. Some women start to increase the daily dosage to 2 capsules (1000 mg in total) at 36-37 weeks, and to 3 capsules (1500 mg in total) starting at week 38. Evening primrose oil or other omega-6 fatty acids should be avoided by anyone who suffers a seizure disorder or bleeding problems. Evening primrose oil can help with conditions such as arthritis for older dogs, as well as the pain and discomfort of dry, itchy skin. Bleeding may occur. aging. If the supplement is taken in liquid form, then obviously the doses are different. READ >>> Evening primrose oil for menopause – reviews, dosage, and effects. No toxicity, carcinogenicity, or teratogenicity has been reported. A case report exists of transient petechiae in a newborn following oral and intravaginal use of evening primrose oil for cervical ripening for a week prior to the infant's birth. 1,3 Today, this oil is commonly used as a carrier oil for essential oils but carries its own benefits, as well. A typical dosage of evening primrose oil, standardized to contain eight percent GLA, is two to eight grams per day. Last updated on Feb 28, 2020. Therefore, always pay attention to the information on the label regarding the oil content. Scientific Name(s): Oenothera biennis L.Common Name(s): Common evening primrose, Evening primrose. The recommended dose is 500mg of evening primrose oil capsule daily or 360 mg to 480 mg GLA from evening primrose oil daily for six months. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Evening primrose oil is a herbal supplement that comes from the evening primrose plant. Disease Dosage Frequency; acne. Wide-ranging doses of 0.27 g to 6.48 g GLA per day have been used in clinical studies in mastalgia.24 The typical content of GLA in the oil is 8% to 10%.2, Evening primrose oil 1 g/day in combination with vitamin D3 (1,000 units/day) has been used to improve glycemic and lipid profiles in women with gestational diabetes.70, Information regarding safety and efficacy in pregnancy and lactation is lacking. For example, to cover the daily need of 3000 mg with 500mg capsules, you would have to take 6 capsules per day. Side effects, drug interactions, dosage, storage, and safety information should be reviewed prior to taking this supplement. Evening Primrose Oil Side Effects. Get the best articles straight into your inbox before everyone else! Since evening primrose oil is a nutritional supplement, there is no recommended daily amount set for its use. The oil pressed from its seeds, aka evening primrose oil (EPO for short), is a gentle carrier oil. Evening primrose oil can help with conditions such as arthritis for older dogs, as well as the pain and discomfort of dry, itchy skin. There is no official upper limit for EPO, but the European Medicines Agency warns that children under 12 should not take it.17 You should also avoid taking EPO if you:18 1. are on blood thinning drugs like warfarin, as EPO has blood-thinning effects 2. are due to have surgery in two weeks 3. have epilepsy, s… So 500mg twice a day or three times a day. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. Although proponents claim that this oil may help with conditions such as eczema, dry eye, chronic pain, and women’s hormonal issues, there is insufficient evidence to support most uses. There are no further reports of seizures related to evening primrose oil, which may actually have a protective effect.63, A case report of lipoid pneumonia secondary to long-term evening primrose oil use exists.64, There is no recent evidence to support older studies suggesting that evening primrose oil reduced platelet aggregation.38, 39, 40, Animal toxicological studies and extensive use of evening primrose oil over many years revealed no data of concern. The most common side effects are temporary gastrointestinal symptoms such as abdominal pain, fullness, or nausea. Bleeding may occur. Topical application of evening primrose oil is used to relieve pain, but its efficacy for nerve pain has not been ascertained. Learn its uses and side-effects when treating rheumatoid arthritis. Starting around 37 weeks insert 1 capsule (500 mg) vaginally every evening before going to bed. Evening primrose oil may be safe for use during pregnancy and while breastfeeding, but the evidence is not conclusive. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. Evidence suggests that evening primrose oil may be effective for treating rheumatoid arthritis, injection site skin reactions, and diabetic neuropathy, but is lacking to support its place in the treatment of atopic eczema/dermatitis syndrome, menopausal vasomotor symptoms, mastalgia, or multiple sclerosis. Consider therapy modification.59, 60, 61, 62, Nonsteroidal anti-inflammatory agents: Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of nonsteroidal anti-inflammatory agents. Contents of evening primrose oil per capsule may be different for different brands. Our range makes it easy to select the best omega oil product to support your body from the inside out. This oil is also good for other inflammatory conditions of the skin, such as psoriasis and eczema, and can protect wounds and cuts from infection. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. In some cases, the dose could be increased to 1-3  capsules per day (no more than 3000mg). Both linoleic and GLA are normally present in breast milk, and it is reasonable to assume that evening primrose oil may be taken while breast-feeding. Too high of an evening primrose oil dosage can result in stomach pain, headache and diarrhea. Most women develop breast pain (mastalgia) at some stage in life. And the 1300mg content of GLA will cover your daily need with 2 capsules only. In cancer studies, … Evening primrose oil dosage: The dosage usually depends on what you are taking it for and varies widely depending on where you are doing your research. Look for high-quality evening primrose oil certified as organic by a reputable third party. Evening primrose oil is generally safe when used in recommended dosages, which is 2 to 8 grams daily. Possible side effects of evening primrose oil for weight loss Negative effects from taking evening primrose oil for weight loss are mild digestive issues and headaches. Studies conducted in children with dyslexia suggest improved reading, spelling, and behavior45, 46 while a Cochrane systematic review and a long-term study (39 months) showed no long-term benefit in infants fed formula supplemented with long-chain polyunsaturated fatty acids.47, 48 An open study found benefit with the use of a fish oil and evening primrose oil combination in children with dyslexia.49, Study results disagree as to the effect of evening primrose oil on dry eye syndrome37, 50, 51 and there is concern regarding high intake of linoleic and linolenic acid and the risk of cataract development.52, 53, A prospective, double-blind, randomized placebo-controlled trial in 60 Iranian women with gestational diabetes mellitus investigated the effect of vitamin D3 (1,000 units) plus evening primrose oil (1,000 mg) on insulin resistance and lipid parameters. In most cases, evening primrose oil side effects are linked to excess use, impurities in the oil and improper usage. The GLA in EPO is thought to help acne by reducing skin inflammation … Used as recommended, EPO is generally considered safe. Oenothera (Evening primrose oil, Fever plant, Sun drops) is an herbal supplement used for its anti-inflammatory and pain-relieving effects. This website is supported by different affiliates and we receive a paid commission on certain products from our advertisers. The recommended dose of evening primrose oil is 8 to 12 capsules a day, at a dose of 500 milligrams per capsule. Evidence for the effectiveness of EPO in reducing joint pain in rheumatoid arthritis isn’t conclusive, but there’s some evidence that it can improve morning stiffness. Evening primrose oil is generally well tolerated. Medscape - Indication-specific dosing for fever plant, kings cureall, night willow herb, oenothera biennis, scabish, stella di sera, sun drop (evening primrose oil), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Evening Primrose Oil Dosage may vary from 500 mg to 3000mg depending on the health condition. The dose is calculated on the basis of a clinical study [1]. Modern medicine uses the oil extract from evening primrose seeds in supplements to treat eczema, breast pain, and menopausal symptoms. Acne dosage equals to 1000mg daily previously suspected to lower the seizure threshold in schizophrenic ;. ( pain-relieving ) properties low dose, evening primrose oil [ 31 ] on more 24,000. Medical studies estimate dosage of evening primrose oil per day the speed with which decompose... Breast pain, but the evidence is not considered to be the or! 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